Effects of Acute 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exposure on the Circulating and Cecal Metabolome Profile

Effects of Acute 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exposure on the Circulating and Cecal Metabolome Profile

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a polyhalogenated planar hydrocarbon belonging to a group of highly toxic and persistent environmental contaminants known as “dioxins”. TCDD is an animal teratogen and carcinogen that is well characterized for causing immunosuppression through activation...

Full description

Bibliographic Details
Main Authors: Nicholas Dopkins, Wurood Hantoosh Neameh, Alina Hall, Yunjia Lai, Alex Rutkovsky, Alexa Orr Gandy, Kun Lu, Prakash S. Nagarkatti, Mitzi Nagarkatti
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
2,3,7,8-tetrachlorodibenzo-p-dioxin
toxicity
NFκB
aryl hydrocarbon receptor
metabolome
immunity
Online Access:https://www.mdpi.com/1422-0067/22/21/11801

Internet

https://www.mdpi.com/1422-0067/22/21/11801

Similar Items