Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens.

Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens.

<h4>Background</h4>Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern o...

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Autori principali: Cindy S Chu, Germana Bancone, Kerryn A Moore, Htun Htun Win, Niramon Thitipanawan, Christina Po, Nongnud Chowwiwat, Rattanaporn Raksapraidee, Pornpimon Wilairisak, Aung Pyae Phyo, Lily Keereecharoen, Stéphane Proux, Prakaykaew Charunwatthana, François Nosten, Nicholas J White
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2017-02-01
Serie:PLoS Medicine
Accesso online:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1002224&type=printable

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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1002224&type=printable

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