Identification of DNA damage response-related genes as biomarkers for castration-resistant prostate cancer

Abstract Although hormone therapy is effective for the treatment of prostate cancer (Pca), many patients develop a lethal type of Pca called castration-resistant prostate cancer (CRPC). Dysregulation of DNA damage response (DDR)-related genes leads to Pca progression. Here, we explored DDR-related s...

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Bibliographic Details
Main Authors: Masashi Oshima, Ken-ichi Takayama, Yuta Yamada, Naoki Kimura, Haruki Kume, Tetsuya Fujimura, Satoshi Inoue
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46651-6