Using AI-Based Evolutionary Algorithms to Elucidate Adult Brain Tumor (Glioma) Etiology Associated with IDH1 for Therapeutic Target Identification

Using AI-Based Evolutionary Algorithms to Elucidate Adult Brain Tumor (Glioma) Etiology Associated with IDH1 for Therapeutic Target Identification

Adult brain tumors (glioma) represent a cancer of unmet need where standard-of-care is non-curative; thus, new therapies are urgently needed. It is unclear whether isocitrate dehydrogenases (IDH1/2) when not mutated have any role in gliomagenesis or tumor growth. Nevertheless, IDH1 is overexpressed...

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Bibliographic Details
Main Authors: Caitríona E. McInerney, Joanna A. Lynn, Alan R. Gilmore, Tom Flannery, Kevin M. Prise
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Current Issues in Molecular Biology
Subjects:
glioblastoma
brain cancer
glioma
biomarker
artificial intelligence
evolutionary algorithm
Online Access:https://www.mdpi.com/1467-3045/44/7/206

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https://www.mdpi.com/1467-3045/44/7/206

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