Triptolide Suppresses NF-κB-Mediated Inflammatory Responses and Activates Expression of Nrf2-Mediated Antioxidant Genes to Alleviate Caerulein-Induced Acute Pancreatitis

Triptolide Suppresses NF-κB-Mediated Inflammatory Responses and Activates Expression of Nrf2-Mediated Antioxidant Genes to Alleviate Caerulein-Induced Acute Pancreatitis

Triptolide (TP), the main active ingredient of <i>Tripterygium wilfordii Hook.f.</i>, displays potent anti-inflammatory, antioxidant, and antiproliferative activities. In the present study, the effect of TP on acute pancreatitis and the underlying mechanisms of the disease were investiga...

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Bibliographic Details
Main Authors: Jing Yang, Xujiao Tang, Xue Ke, Yutong Dai, Jinsong Shi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
acute pancreatitis
triptolide
inflammatory responses
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/23/3/1252

Internet

https://www.mdpi.com/1422-0067/23/3/1252

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