Synthesis and Cytotoxic Evaluation of a Series of 2-Amino-Naphthoquinones against Human Cancer Cells

Synthesis and Cytotoxic Evaluation of a Series of 2-Amino-Naphthoquinones against Human Cancer Cells

The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 (ovarian), NCI-H358M (bronchoalveolar lung carcinom...

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Bibliographic Details
Main Authors: Thiago A. P. de Moraes, Maria J. S. Filha, Celso A. Camara, Tania M. S. Silva, Bruno M. Soares, Igor S. Bomfim, Claudia Pessoa, George C. Ximenes, Valdemiro A. Silva
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
naphthoquinones
aminoacid naphthoquinones
cytotoxicity
cancer cells
Online Access:http://www.mdpi.com/1420-3049/19/9/13188

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http://www.mdpi.com/1420-3049/19/9/13188

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