IKKγ/NEMO Localization into Multivesicular Bodies

IKKγ/NEMO Localization into Multivesicular Bodies

The NF-κB pathway is central pathway for inflammatory and immune responses, and IKKγ/NEMO is essential for NF-κB activation. In a previous report, we identified the role of glycogen synthase kinase-3β (GSK-3β) in NF-κB activation by regulating IKKγ/NEMO. Here, we show that NEMO phosphorylation by GS...

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Bibliographic Details
Main Authors: Lisa-Marie Wackernagel, Mohsen Abdi Sarabi, Sönke Weinert, Werner Zuschratter, Karin Richter, Klaus Dieter Fischer, Ruediger C. Braun-Dullaeus, Senad Medunjanin
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
NF-κB pathway
NF-κB essential modifier (NEMO/IKKγ)
glycogen synthase kinase-3 (GSK-3)
Online Access:https://www.mdpi.com/1422-0067/23/12/6778

Internet

https://www.mdpi.com/1422-0067/23/12/6778

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