Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis

Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis

Abstract Onconeural antibodies are associated with cancer and paraneoplastic encephalitis. While their pathogenic role is still largely unknown, their high diagnostic value is undisputed. In this study we describe the discovery of a novel target of autoimmunity in an index case of paraneoplastic enc...

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Bibliographic Details
Main Authors: Stoyan Popkirov, Ilya Ayzenberg, Stefanie Hahn, Jan Bauer, Yvonne Denno, Nicole Rieckhoff, Christiane Radzimski, Volkmar H. Hans, Sebastian Berg, Florian Roghmann, Joachim Noldus, Christian G. Bien, Sabine Skodda, Jörg Wellmer, Winfried Stöcker, Christos Krogias, Ralf Gold, Uwe Schlegel, Christian Probst, Lars Komorowski, Ramona Miske, Ingo Kleiter
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Acta Neuropathologica Communications
Subjects:
Paraneoplastic encephalitis
Status epilepticus
Autoantibody
Rho-associated protein kinase 2
Urogential cancer
Online Access:http://link.springer.com/article/10.1186/s40478-017-0447-3

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http://link.springer.com/article/10.1186/s40478-017-0447-3

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