New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals — a PARC (Partnership for the Assessment of Risk from Chemicals) project

New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals — a PARC (Partnership for the Assessment of Risk from Chemicals) project

As a complex system governing and interconnecting numerous functions within the human body, the immune system is unsurprisingly susceptible to the impact of toxic chemicals. Toxicants can influence the immune system through a multitude of mechanisms, resulting in immunosuppression, hypersensitivity,...

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Bibliographic Details
Main Authors: Igor Snapkow, Nicola M. Smith, Emma Arnesdotter, Karsten Beekmann, Etienne B. Blanc, Albert Braeuning, Emanuela Corsini, Marija Sollner Dolenc, Loes P. M. Duivenvoorde, Gunnar Sundstøl Eriksen, Nina Franko, Valentina Galbiati, Johanna M. Gostner, Nathalie Grova, Arno C. Gutleb, Rita Hargitai, Aafke W. F. Janssen, Solveig A. Krapf, Birgitte Lindeman, Katalin Lumniczky, Ambra Maddalon, Steen Mollerup, Lucia Parráková, Arkadiusz Pierzchalski, Raymond H. H. Pieters, Maria J. Silva, Anita Solhaug, Yvonne C. M. Staal, Anne Straumfors, Tünde Szatmári, Jonathan D. Turner, Rob J. Vandebriel, Ana Claudia Zenclussen, Robert Barouki
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Toxicology
Subjects:
PARC
new approach methodologies
NAMs
immunotoxicology
immunosuppression
regulatory toxicology
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1339104/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2024.1339104/full

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