An Efficient Preparation of 1,2-Diamino-1-phenylheptane

A convenient four-step method for the preparation of the lipophilic vicinal diamine 1,2-diamino-1-phenylheptane is described. Condensation involving octan-2-one, benzaldehyde and ammonia is reported. Regioselective Schmidt rearrangement of 2,6-diphenyl-3-pentyl-piperidin-4-one (1) to 2,7-diphenyl-3-...

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Bibliographic Details
Main Authors: P. T. Perumal, S. Thennarasu
Format: Article
Language:English
Published: MDPI AG 2002-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/7/6/487/