A Single Injection with Sustained-Release Microspheres and a Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG Antibody Response in Mice

A Single Injection with Sustained-Release Microspheres and a Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG Antibody Response in Mice

Although vaccination is still considered to be the cornerstone of public health care, the increase in vaccination coverage has stagnated for many diseases. Most of these vaccines require two or three doses to be administered across several months or years. Single-injection vaccine formulations are a...

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Bibliographic Details
Main Authors: Renée S. van der Kooij, Martin Beukema, Anke L. W. Huckriede, Johan Zuidema, Rob Steendam, Henderik W. Frijlink, Wouter L. J. Hinrichs
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
bovine serum albumin
immune response
monolithic microspheres
multi-block copolymer
single-injection vaccine
sustained release
Online Access:https://www.mdpi.com/1999-4923/15/2/676

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https://www.mdpi.com/1999-4923/15/2/676

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