Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN), or NAD itself. We provide evidence that murin...

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Bibliographic Details
Main Authors: Antonio Davila, Ling Liu, Karthikeyani Chellappa, Philip Redpath, Eiko Nakamaru-Ogiso, Lauren M Paolella, Zhigang Zhang, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
NAD
NADH
nicotinamide
niacin
mononucleotide
mitochondria
Online Access:https://elifesciences.org/articles/33246

Internet

https://elifesciences.org/articles/33246

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