GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling

GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling

Summary: Regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (FoxP3) control immune responses and prevent autoimmunity. Treatment with glucocorticoids (GCs) has been shown to increase Treg cell frequency, but the mechanisms of their action on Treg cell induction are largely...

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Bibliographic Details
Main Authors: Oxana Bereshchenko, Maddalena Coppo, Stefano Bruscoli, Michele Biagioli, Monica Cimino, Tiziana Frammartino, Daniele Sorcini, Alessandra Venanzi, Moises Di Sante, Carlo Riccardi
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714001661

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http://www.sciencedirect.com/science/article/pii/S2211124714001661

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