Replacement of osmotic minipumps to extend the intracerebral infusion time of compounds into the mouse brain

Osmotic minipumps represent a convenient and established method for targeted delivery of agents into the brain of small rodents. Agents unable to cross the blood brain barrier can be directly infused into the brain parenchyma or lateral ventricle through implanted cannulas. The small volume of the m...

Full description

Bibliographic Details
Main Authors: Stefan A. Grathwohl, Mathias Jucker
Format: Article
Language:English
Published: Taylor & Francis Group 2013-08-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/000114064