RISK and SAFE signaling pathway involvement in apolipoprotein A-I-induced cardioprotection.

Recent findings indicate that apolipoprotein A-I (ApoA-I) may be a protective humoral mediator involved in remote ischemic preconditioning (RIPC). This study sought to determine if ApoA-I mediates its protective effects via the RISK and SAFE signaling pathways implicated in RIPC. Wistar rats were al...

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Bibliographic Details
Main Authors: Hussein Kalakech, Pierre Hibert, Delphine Prunier-Mirebeau, Sophie Tamareille, Franck Letournel, Laurent Macchi, Florence Pinet, Alain Furber, Fabrice Prunier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169577?pdf=render