Safety of dofetilide in stable patients and investigating traits of susceptibility to torsade de pointes

Safety of dofetilide in stable patients and investigating traits of susceptibility to torsade de pointes

Background: Atrial fibrillation is the most prevalent cardiac arrhythmia, presenting symptomatic patients with diminished quality of life and worsening of heart failure. Dofetilide, a class 3 antiarrhythmic agent, is a proven and safe rhythm control medication. Initial risk of QT prolongation leadin...

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Bibliographic Details
Main Authors: Maria Cecilia Tagle-Cornell, Chadi Ayoub, Christen Bird, Milagros Pereyra, Courtney Kenyon, Moaz Kamel, Shruti Iyengar, Hema Vemulapalli, Francesca Galasso, Marlene Girardo, Klanderman Molly, Komandoor Srivathsan
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
Dofetilide
Atrial fibrillation
Risk factors
Torsade de pointes
Polymorphic ventricular tachycardia
Incidence of TdP in women
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906724001416

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http://www.sciencedirect.com/science/article/pii/S2352906724001416

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