Metabotropic glutamate receptor genetic variants and peripheral receptor expression affects trait scores of autistic probands

Abstract Glutamate (Glu) is important for memory and learning. Hence, Glu imbalance is speculated to affect autism spectrum disorder (ASD) pathophysiology. The action of Glu is mediated through receptors and we analyzed four metabotropic Glu receptors (mGluR/GRM) in Indo-Caucasoid families with ASD...

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Bibliographic Details
Main Authors: Nilanjana Dutta, Mahasweta Chatterjee, Sharmistha Saha, Swagata Sinha, Kanchan Mukhopadhyay
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-59290-2