Binary and analog variation of synapses between cortical pyramidal neurons

Binary and analog variation of synapses between cortical pyramidal neurons

Learning from experience depends at least in part on changes in neuronal connections. We present the largest map of connectivity to date between cortical neurons of a defined type (layer 2/3 [L2/3] pyramidal cells in mouse primary visual cortex), which was enabled by automated analysis of serial sec...

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Bibliographic Details
Main Authors: Sven Dorkenwald, Nicholas L Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Agnes L Bodor, Adam A Bleckert, Derrick Brittain, Nico Kemnitz, William M Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Szi-Chieh Yu, Sergiy Popovych, William Wong, Manuel Castro, Chris S Jordan, Alyssa M Wilson, Emmanouil Froudarakis, JoAnn Buchanan, Marc M Takeno, Russel Torres, Gayathri Mahalingam, Forrest Collman, Casey M Schneider-Mizell, Daniel J Bumbarger, Yang Li, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S Tolias, Nuno Macarico da Costa, R Clay Reid, H Sebastian Seung
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-11-01
Series:eLife
Subjects:
synapses
connectivity diagram
pyramidal cell
electron microscopy
Online Access:https://elifesciences.org/articles/76120

Internet

https://elifesciences.org/articles/76120

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