High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Fusion-positive RMS (FPRMS), expressing the PAX3/7-FOXO1, has a worse prognosis compared to the more common fusion-negative RMS (FNRMS). Although several studies reported hierarchical organization for FNRMS with the identific...

Full description

Bibliographic Details
Main Authors: Melanie Generali, Sampoorna Satheesha, Peter K. Bode, Debora Wanner, Beat W. Schäfer, Elisa A. Casanova
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/9/1373