Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hyperinsulinemic euglycemic clamp

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hyperinsulinemic euglycemic clamp

BackgroundSkeletal muscle is the main site for insulin-dependent glucose disposal. The hyperinsulinemic euglycemic clamp (HIEC) is the gold standard for the assessment of insulin sensitivity (IS). We have previously shown that insulin sensitivity, measured by HIEC, varied widely among a group of 60...

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Bibliographic Details
Main Authors: Ilham Bettahi, Roopesh Krishnankutty, Morana Jaganjac, Noor Nabeel M. Suleiman, Manjunath Ramanjaneya, Jayakumar Jerobin, Shaimaa Hassoun, Meis Alkasem, Ibrahem Abdelhakam, Ahmad Iskandarani, Tareq A. Samra, Vidya Mohamed-Ali, Abdul Badi Abou-Samra
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
insulin sensitivity
insulin resistance
HIEC
proteomics
mitochondria
diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1024832/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1024832/full

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