Integrating network analysis and experimental validation to reveal the mitophagy-associated mechanism of Yiqi Huoxue (YQHX) prescription in the treatment of myocardial ischemia/reperfusion injury

Integrating network analysis and experimental validation to reveal the mitophagy-associated mechanism of Yiqi Huoxue (YQHX) prescription in the treatment of myocardial ischemia/reperfusion injury

Myocardial ischemia/reperfusion (I/R) injury is the main cause of increasing postischemic heart failure and currently there is no definite treatment for myocardial I/R injury. It has been suggested that oxidative stress-induced mitochondrial dysfunction plays an important role in the pathological de...

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Bibliographic Details
Main Authors: Mingtai Chen, Guofu Zhong, Mengnan Liu, Hao He, Jie Zhou, Jianping Chen, Mingsheng Zhang, Qiang Liu, Guangdong Tong, Jienan Luan, Hua Zhou
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Pharmacological Research
Subjects:
Myocardial ischemia/reperfusion injury
Yiqi Huoxue
Mitophagy
Network pharmacology
Traditional Chinese medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823000385

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http://www.sciencedirect.com/science/article/pii/S1043661823000385

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