Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells

Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells

Many solid tumours (e.g. sarcoma, carcinoma and lymphoma) form a disorganized neo-vasculature that initiates uncontrolled vessel formation to support tumour growth. The complexity of these environments poses a significant challenge for tumour medicine research. While animal models are commonly used...

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Bibliographic Details
Main Authors: Lisa Asciak, Lauren Gilmour, Jonathan A. Williams, Euan Foster, Lara Díaz-García, Christopher McCormick, James F. C. Windmill, Helen E. Mulvana, Joseph C. Jackson-Camargo, Roger Domingo-Roca
Format: Article
Language:English
Published: The Royal Society 2023-08-01
Series:Royal Society Open Science
Subjects:
neo-vasculature
three-dimensional printing
tissue-mimicking
animal replacement
nitric oxide
endothelial cells
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.230929

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https://royalsocietypublishing.org/doi/10.1098/rsos.230929

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