The Search for Biomarkers and Treatments in Chagas Disease: Insights From TGF-Beta Studies and Immunogenetics

The Search for Biomarkers and Treatments in Chagas Disease: Insights From TGF-Beta Studies and Immunogenetics

The anti-inflammatory cytokine transforming growth factor beta (TGF-β) plays an important role in Chagas disease (CD), a potentially life-threatening illness caused by Trypanosoma cruzi. In this review we revisited clinical studies in CD patients combined with in vitro and in vivo experiments, prese...

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Bibliographic Details
Main Authors: Roberto Rodrigues Ferreira, Mariana Caldas Waghabi, Sabine Bailly, Jean-Jacques Feige, Alejandro M. Hasslocher-Moreno, Roberto M. Saraiva, Tania C. Araujo-Jorge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chagas disease
TGF-beta
fibrosis
biomarker
polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.767576/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.767576/full

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