Panoramic comparison between NK cells in healthy and cancerous liver through single-cell RNA sequencing

Panoramic comparison between NK cells in healthy and cancerous liver through single-cell RNA sequencing

Objective: NK cells play crucial roles in the immune defense mechanisms against viral infections and transformed cells. However, the developmental progression, transcriptomic landscape, and functional subtypes of liver NK cells are not well defined. Hepatocellular carcinoma (HCC) accounts for approx...

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Bibliographic Details
Main Authors: Huan Liu, Ronghua Zhao, Rongrong Qin, Haoyu Sun, Qiang Huang, Lianxin Liu, Zhigang Tian, Björn Nashan, Cheng Sun, Rui Sun
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-09-01
Series:Cancer Biology & Medicine
Subjects:
hepatocellular carcinoma
natural killer cell
single-cell rna sequencing
heterogeneity
prognosis
Online Access:https://www.cancerbiomed.org/content/19/9/1334

Internet

https://www.cancerbiomed.org/content/19/9/1334

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