Opioid sparing effect of intravenous dexmedetomidine in orthopaedic surgery: a retrospective analysis

Abstract Background Dexmedetomidine is a highly selective alpha-2 receptor agonist without any effect on the GABA receptor. It provides an excellent sedative and analgesic profile with few side effects. We report our experience with dexmedetomidine use during orthopaedic surgery under locoregional a...

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Bibliographic Details
Main Authors: Valerio Donatiello, Aniello Alfieri, Andrea Napolitano, Vincenzo Maffei, Francesco Coppolino, Vincenzo Pota, Maria Beatrice Passavanti, Maria Caterina Pace, Pasquale Sansone
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Anesthesia, Analgesia and Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s44158-022-00076-1