Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis

Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis

Abstract Epigenetic alterations, especially histone methylation, are key factors in cell migration and invasion in cancer metastasis. However, in lung cancer metastasis, the mechanism by which histone methylation regulates metastasis has not been fully elucidated. Here, we found that the histone met...

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Bibliographic Details
Main Authors: Kwangho Kim, Tae Young Ryu, Eunsun Jung, Tae-Su Han, Jinkwon Lee, Seon-Kyu Kim, Yu Na Roh, Moo-Seung Lee, Cho-Rok Jung, Jung Hwa Lim, Ryuji Hamamoto, Hye Won Lee, Keun Hur, Mi-Young Son, Dae-Soo Kim, Hyun-Soo Cho
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00987-1

Internet

https://doi.org/10.1038/s12276-023-00987-1

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