Well-balanced immune response and protective efficacy induced by a single dose of live attenuated tetravalent dengue vaccine (KD-382) in monkeys

Well-balanced immune response and protective efficacy induced by a single dose of live attenuated tetravalent dengue vaccine (KD-382) in monkeys

One of the challenges developing a live attenuated tetravalent dengue vaccine (TDV) is to overcome the presumed viral interference that may be preventing the induction of a balanced immune response to all 4 serotypes of the dengue virus (DENV1–4). Our live attenuated TDV candidate was developed from...

Full description

Bibliographic Details
Main Authors: Masaya Yoshimura, Yasuhiko Shinmura, Shota Takagi, Kazuhisa Kameyama, Kengo Sonoda, Fusataka Koide, Sutee Yoksan, Kazuhiko Kimachi
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Microbiology
Virology
Antibody
Immune response
Vaccination
Vaccines
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020313505

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020313505

Similar Items