A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases
Bacteria adapt to changing environmental conditions through signal transduction mediated by the two-component system (TCS). Here, the authors combine X-ray crystallography and NMR studies to characterize a pH-gated conformational switch that regulates the phosphatase activity of TCS bifunctional his...
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Portfolio
2017-12-01
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| श्रृंखला: | Nature Communications |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41467-017-02310-9 |