Synthesis of N, N, N-trimethyl chitosan-based nanospheres for the prolonged release of curcumin

It is critical to develop a hydrophilic drug carrier with positive charge on the surface to enhance the bioavailability of curcumin to overcome the tissue barrier, e.g., blood brain barrier. In this paper, a quaternized chitosan derivative, N,N,N-Trimethyl Chitosan (TMC) was produced which is a cati...

Full description

Bibliographic Details
Main Authors: Xueqin Zhao, Chao Lu, Songlin Yang, Rui Ni, Tianqing Peng, Jin Zhang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Food Hydrocolloids for Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667025922000395