The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

Abstract Background Neurotensin, originally isolated in 1973 has both endocrine and neuromodulator activity and acts through its three main receptors. Their role in promoting tumour cell proliferation, migration, DNA synthesis has been studied in a wide range of cancers. Expression of Neurotensin an...

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Библиографические подробности
Главные авторы: Stella Nikolaou, Shengyang Qiu, Francesca Fiorentino, Constantinos Simillis, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios
Формат: Статья
Язык:English
Опубликовано: BMC 2020-04-01
Серии:Cell Communication and Signaling
Предметы:
Online-ссылка:http://link.springer.com/article/10.1186/s12964-020-00569-y