Ex vivo permeation parameters and skin deposition of melatonin-loaded microemulsion for treatment of alopecia

Ex vivo permeation parameters and skin deposition of melatonin-loaded microemulsion for treatment of alopecia

Abstract Background Melatonin (MEL) is a powerful antioxidant molecule with anti-androgenic property. A microemulsion (ME) system loaded with MEL was designed for treatment of androgenic alopecia. Pseudo-ternary phase diagram was constructed, and ME formulae were developed using coconut oil, Tween 8...

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Bibliographic Details
Main Authors: Asmaa A. Elshall, Amira M. Ghoneim, Heidi M. Abdel-Mageed, Rihab Osman, Dalia S. Shaker
Format: Article
Language:English
Published: SpringerOpen 2022-05-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Melatonin
Microemulsion
Transdermal
Androgenic alopecia
Topical
Online Access:https://doi.org/10.1186/s43094-022-00418-4

Internet

https://doi.org/10.1186/s43094-022-00418-4

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