Ovarian cancer ascites confers platinum chemoresistance to ovarian cancer cells

Ovarian cancer ascites confers platinum chemoresistance to ovarian cancer cells

Ovarian cancer (OC), the second most common form of gynecologic malignancy, has a poor prognosis and is often discovered in the late stages. Platinum-based chemotherapy is the first line of therapy. Nevertheless, treatment OC has proven challenging due to toxicity and the development of acquired res...

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Bibliographic Details
Main Authors: Yifat Koren Carmi, Abed Agbarya, Hazem Khamaisi, Raymond Farah, Yelena Shechtman, Roman Korobochka, Jacob Gopas, Jamal Mahajna
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Translational Oncology
Subjects:
Ovarian cancer
Platinum chemoresistance
Tumor microenvironment
2-hydroxyestradiol
Crizotinib
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000664

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http://www.sciencedirect.com/science/article/pii/S1936523324000664

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