T cell transcription factor expression evolves over time in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

Summary: Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a global health concern, yearly resulting in 10 million new cases of active TB. Immunologic investigation of lung granulomas is essential for understanding host control of bacterial replication. Here, we identify...

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Bibliographic Details
Main Authors: Nicole L. Grant, Pauline Maiello, Edwin Klein, Philana Ling Lin, H. Jacob Borish, Jaime Tomko, L. James Frye, Alexander G. White, Denise E. Kirschner, Joshua T. Mattila, JoAnne L. Flynn
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005976