Molecular modeling, molecular dynamics simulation, and essential dynamics analysis of grancalcin: An upregulated biomarker in experimental autoimmune encephalomyelitis mice

Molecular modeling, molecular dynamics simulation, and essential dynamics analysis of grancalcin: An upregulated biomarker in experimental autoimmune encephalomyelitis mice

The experimental autoimmune encephalomyelitis mouse model is the most commonly used animal model, and it best represents multiple sclerosis. Grancalcin (GCA) was discovered to be upregulated in EAE mice. GCA comprises 220 amino acids that have been assigned the UniprotKB ID Q8VC88. It is a calcium-b...

Full description

Bibliographic Details
Main Authors: Shamrat Kumar Paul, Md. Saddam, Khandoker Asiqur Rahaman, Jong-Gu Choi, Sang-Suk Lee, Mahbub Hasan
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Heliyon
Subjects:
Molecular dynamics simulation
Principal component analysis
EAE
Multiple sclerosis
Grancalcin
GROMACS
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022025208

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022025208

Similar Items