Causal association between obstructive sleep apnea and amyotrophic lateral sclerosis: a Mendelian randomization study

Causal association between obstructive sleep apnea and amyotrophic lateral sclerosis: a Mendelian randomization study

BackgroundObstructive sleep apnea (OSA) had a high prevalence in the population. Whether OSA increases the risk of amyotrophic lateral sclerosis (ALS) is unknown. Our aim was to clarify this issue using two-sample Mendelian randomization (MR) analysis in a large cohort.MethodsTwo-sample MR was used...

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Bibliographic Details
Main Authors: Rongrong Du, Yahui Zhu, Peng Chen, Mao Li, Ying Zhang, Xusheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
obstructive sleep apnea
amyotrophic lateral sclerosis
causality
genetic association
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1357070/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1357070/full

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