Ancestry-driven metabolite variation provides insights into disease states in admixed populations

Ancestry-driven metabolite variation provides insights into disease states in admixed populations

Abstract Background Metabolic pathways are related to physiological functions and disease states and are influenced by genetic variation and environmental factors. Hispanics/Latino individuals have ancestry-derived genomic regions (local ancestry) from their recent admixture that have been less char...

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Bibliographic Details
Main Authors: Kaylia M. Reynolds, Andrea R. V. R. Horimoto, Bridget M. Lin, Ying Zhang, Nuzulul Kurniansyah, Bing Yu, Eric Boerwinkle, Qibin Qi, Robert Kaplan, Martha Daviglus, Lifang Hou, Laura Y. Zhou, Jianwen Cai, Saame Raza Shaikh, Tamar Sofer, Sharon R. Browning, Nora Franceschini
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Genome Medicine
Subjects:
Admixture mapping
Local ancestry
Metabolites
Hispanics/Latino populations
Online Access:https://doi.org/10.1186/s13073-023-01209-z

Internet

https://doi.org/10.1186/s13073-023-01209-z

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