ASSESSING THE EFFECT OF OUTER MEMBRANE PERMEABILIZATION FOR POTENTIATING THE ANTIBACTERIAL ACTIVITY OF CEFIDEROCOL ON PSEUDOMONAS AERUGINOSA
Intro: Pseudomonas aeruginosa is an opportunistic pathogen that causes lifethreatening infections. Cefiderocol (CFDC), a new siderophore-cephalosporin, utilizes iron transport systems to penetrate bacterial outer membrane (OM). Resistance can occur due to mutations in these systems reducing drug upt...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-08-01
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Series: | International Journal of Infectious Diseases |
Online Access: | http://www.sciencedirect.com/science/article/pii/S120197122300601X |