ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling

ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling

Epithelial-mesenchymal transition (EMT) is a cellular process by which epithelial cells transform to acquire mesenchymal phenotypes. Accumulating evidence indicate the involvement of EMT in the progression of malignant diseases. Notch signaling mediates TGF-β1-induced EMT through direct transcriptio...

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Bibliographic Details
Main Authors: Kai Yazaki, Yosuke Matsuno, Kazufumi Yoshida, Mingma Sherpa, Masayuki Nakajima, Masashi Matsuyama, Takumi Kiwamoto, Yuko Morishima, Yukio Ishii, Nobuyuki Hizawa
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:European Journal of Cell Biology
Subjects:
EMT
TGF-β1
Notch signaling
ROS
Nrf2
A549
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933521000327

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http://www.sciencedirect.com/science/article/pii/S0171933521000327

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