Casein kinase 1 alpha regulates chromosome congression and separation during mouse oocyte meiotic maturation and early embryo development.

Casein kinase I alpha (CK1α) is a member of serine/threonine protein kinase, generally present in all eukaryotes. In mammals, CK1α regulates the transition from interphase to metaphase in mitosis. However, little is known about its role in meiosis. Here we examined Ck1α mRNA and protein expression,...

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Bibliographic Details
Main Authors: Lu Wang, Angeleem Lu, Hong-Xia Zhou, Ran Sun, Jie Zhao, Cheng-Jie Zhou, Jiang-Peng Shen, Sha-Na Wu, Cheng-Guang Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3655170?pdf=render