Non-viral chimeric antigen receptor (CAR) T cells going viral

Non-viral chimeric antigen receptor (CAR) T cells going viral

Chimeric antigen receptor (CAR) T cell therapy has made significant strides in the treatment of B-cell malignancies, but its application in treating solid tumors still poses significant challenges. Particularly, the widespread use of viral vectors to deliver CAR transgenes into T cells comes with li...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: H. Balke-Want, V. Keerthi, A. Cadinanos-Garai, C. Fowler, N. Gkitsas, A.K. Brown, R. Tunuguntla, M. Abou-el-Enein, S.A. Feldman
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Elsevier 2023-06-01
Saila:Immuno-Oncology and Technology
Gaiak:
cell therapy scaling
CRISPR
electroporation
gene delivery
manufacturing
non-viral CAR T cells
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2590018823000035

Internet

http://www.sciencedirect.com/science/article/pii/S2590018823000035

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