Non-viral chimeric antigen receptor (CAR) T cells going viral

Non-viral chimeric antigen receptor (CAR) T cells going viral

Chimeric antigen receptor (CAR) T cell therapy has made significant strides in the treatment of B-cell malignancies, but its application in treating solid tumors still poses significant challenges. Particularly, the widespread use of viral vectors to deliver CAR transgenes into T cells comes with li...

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Bibliographic Details
Main Authors:	H. Balke-Want, V. Keerthi, A. Cadinanos-Garai, C. Fowler, N. Gkitsas, A.K. Brown, R. Tunuguntla, M. Abou-el-Enein, S.A. Feldman
Format:	Article
Language:	English
Published:	Elsevier 2023-06-01
Series:	Immuno-Oncology and Technology
Subjects:	cell therapy scaling CRISPR electroporation gene delivery manufacturing non-viral CAR T cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590018823000035

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