Chemotherapy dose per kilogram lean body mass increased dose-limiting toxicity event in male head and neck cancer with taxane and platinum-based induction therapy

Chemotherapy dose per kilogram lean body mass increased dose-limiting toxicity event in male head and neck cancer with taxane and platinum-based induction therapy

Abstract Background This study aimed to determine whether drug doses per kilogram of lean body mass (LBM) were associated with dose-limiting toxicity (DLT) events in head and neck cancer (HNC) patients. Methods This retrospective cohort study included 179 HNC patients who underwent induction chemoth...

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Bibliographic Details
Main Authors: Chuan-Jen Hung, Bor-Hwang Kang, Keng-Ming Chang, Ying-Ying Kang, Chun-Hao Yin, Ching-Chih Lee
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Cancer
Subjects:
Head and neck cancer
Induction chemotherapy
Body composition factor
Chemotherapy dose per kilogram lean body mass
Online Access:https://doi.org/10.1186/s12885-022-10152-y

Internet

https://doi.org/10.1186/s12885-022-10152-y

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