Dynamics in a delayed diffusive cell cycle model

In this paper, we construct a delayed diffusive model to explore the spatial dynamics of cell cycle in G2/M transition. We first obtain the local stability of the unique positive equilibrium for this model, which is irrelevant to the diffusion. Then, through investigating the delay-induced Hopf bifu...

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Detalhes bibliográficos
Main Authors: Yanqin Wang, Ling Yang, Jie Yan
Formato: Artigo
Idioma:English
Publicado em: Vilnius University Press 2018-10-01
Colecção:Nonlinear Analysis
Assuntos:
Acesso em linha:http://www.zurnalai.vu.lt/nonlinear-analysis/article/view/13159
Descrição
Resumo:In this paper, we construct a delayed diffusive model to explore the spatial dynamics of cell cycle in G2/M transition. We first obtain the local stability of the unique positive equilibrium for this model, which is irrelevant to the diffusion. Then, through investigating the delay-induced Hopf bifurcation in this model, we establish the existence of spatially homogeneous and inhomogeneous bifurcating periodic solutions. Applying the normal form and center manifold theorem of functional partial differential equations, we also determine the stability and direction of these bifurcating periodic solutions. Finally, numerical simulations are presented to validate our theoretical results.
ISSN:1392-5113
2335-8963