Sex-Dependent Effects of Piromelatine Treatment on Sleep-Wake Cycle and Sleep Structure of Prenatally Stressed Rats

Sex-Dependent Effects of Piromelatine Treatment on Sleep-Wake Cycle and Sleep Structure of Prenatally Stressed Rats

Prenatal stress (PNS) impairs the circadian rhythm of the sleep/wake cycle. The melatonin (MT) analogue Piromelatine (Pir) was designed for the treatment of insomnia. The present study aimed to explore effects of Pir on circadian rhythmicity, motor activity, and sleep structure in male and female ra...

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Bibliographic Details
Main Authors: Jana Tchekalarova, Lidia Kortenska, Pencho Marinov, Natasha Ivanova
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
prenatal stress
sex
piromelatine
motor activity
sleep/wake cycle
BDNF
Online Access:https://www.mdpi.com/1422-0067/23/18/10349

Internet

https://www.mdpi.com/1422-0067/23/18/10349

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