Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats.

Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats.

Successful drug therapies for treating ocular diseases require effective concentrations of neuroprotective compounds maintained over time at the site of action. The purpose of this work was to assess the efficacy of intravitreal controlled delivery of tauroursodeoxycholic acid (TUDCA) encapsulated i...

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Bibliographic Details
Main Authors: Laura Fernández-Sánchez, Irene Bravo-Osuna, Pedro Lax, Alicia Arranz-Romera, Victoria Maneu, Sergio Esteban-Pérez, Isabel Pinilla, María Del Mar Puebla-González, Rocío Herrero-Vanrell, Nicolás Cuenca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5444790?pdf=render

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http://europepmc.org/articles/PMC5444790?pdf=render

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