Hosts, microbiomes, and the evolution of critical windows

Abstract The absence of microbial exposure early in life leaves individuals vulnerable to immune overreaction later in life, manifesting as immunopathology, autoimmunity, or allergies. A key factor is thought to be a “critical window” during which the host's immune system can “learn” tolerance,...

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Bibliographic Details
Main Authors: C. Jessica E. Metcalf, Burcu Tepekule, Marjolein Bruijning, Britt Koskella
Format: Article
Language:English
Published: Oxford University Press 2022-12-01
Series:Evolution Letters
Subjects:
Online Access:https://doi.org/10.1002/evl3.298