Cellular CARD11 Inhibits the Fusogenic Activity of Newcastle Disease Virus via CBM Signalosome-Mediated Furin Reduction in Chicken Fibroblasts

Cellular CARD11 Inhibits the Fusogenic Activity of Newcastle Disease Virus via CBM Signalosome-Mediated Furin Reduction in Chicken Fibroblasts

Newcastle disease virus (NDV) causes an infectious disease that poses a major threat to poultry health. Our previous study identified a chicken brain-specific caspase recruitment domain-containing protein 11 (CARD11) that was upregulated in chicken neurons and inhibited NDV replication. This raises...

Full description

Bibliographic Details
Main Authors: Wenbin Wang, Qiaolin Wei, Qiqi Hao, Yajie Zhang, Yongshan Li, Youkun Bi, Zhongyuan Jin, Haijin Liu, Xuelan Liu, Zengqi Yang, Sa Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
Newcastle disease virus
CARD11
fusogenic activity
furin
CBM signalosome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.607451/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.607451/full

Similar Items