AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

In the 1940s Charles Huggins reported remarkable palliative benefits following surgical castration in men with advanced prostate cancer, and since then the androgen receptor (AR) has remained the main therapeutic target in this disease. Over the past couple of decades, our understanding of AR-signal...

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Bibliographic Details
Main Authors: Michael T. Schweizer, Evan Y. Yu
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/1/7