PARP-1 Val762Ala polymorphism and risk of cancer: a meta-analysis based on 39 case-control studies.

Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear chromatin-associated enzyme involved in several important cellular processes, particularly in the DNA repair system. PARP-1 rs1136410: C>T is among the most studied polymorphisms and likely involved in human carcinogenesis. However, results from...

Full description

Bibliographic Details
Main Authors: Qin Qin, Jing Lu, Hongcheng Zhu, Liping Xu, Hongyan Cheng, Liangliang Zhan, Xi Yang, Chi Zhang, Xinchen Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4031170?pdf=render