The Dual Role of Smad7 in the Control of Cancer Growth and Metastasis

Smad7 was initially identified as an inhibitor of Transforming growth factor (TGF)-β due mainly to its ability to bind TGF-β receptor type I and prevent TGF-β-associated Smad signaling. More recently, it has been demonstrated that Smad7 can interact with other intracellular proteins and regulate al...

Full description

Bibliographic Details
Main Authors: Carmine Stolfi, Irene Marafini, Veronica De Simone, Francesco Pallone, Giovanni Monteleone
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/12/23774